MadSci Network: Microbiology |
Actually, the enzymatic motors that are used to move cilia are very similar
to the enzymatic motors used to make muscles contract. In both cases, a
group of very long, rigid protein molecules are moved relative to each
other by enzymes called Motor proteins. Motor proteins are
specialized enzymes that attach to long filaments in the cell and crawl
along these filaments using ATP as an energy source. There are three main
groups of motor proteins: Myosins, Dyneins, and Kinesins
. Myosins are the motors used in muscles, and they move on
microfilaments made out of a protein called actin (actin and myosin make up
the majority of the protein found in meat, although both are found in every
cell in the body). Dyneins and Kinesins move along hollow filaments called
microtubules made out of a protein called tubulin, but they move in
opposite directions along the outside of the tube, which requires different
types of motors. Paramecia have actin microfilaments and microtubules
along with all three types of motor proteins, but only one set is
responsible for moving the cilia.
Cilia are composed of special arrays of microtubules called axonemes with 9 double tubes
around 2 single tubes. Looking like bridges between the sets of double
tubes are dyneins which are anchored to one double tube and move along its
neighbor. When activated, the dyneins try to slide the tubules by each
other, causing the whole axoneme to twist and bend. The dyneins only slide
the tubules so far before other proteins called Nexins act like
rubber bands and pull the tubules back to their original places. By
alternating between bending and releasing the axoneme, the cilium develops
a beating motion
which propels the cell. So Paramecia move their
cilia in much the same way that we move our muscles - by using motor
proteins to move long filaments past each other.
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